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The database allows analysis, sorting and searching of membrane proteins based on their structural classification, species, destination membrane, numbers of transmembrane segments and subunits, numbers of secondary structures and the calculated hydrophobic thickness or tilt angle with respect to the bilayer normal. All coordinate files with the calculated membrane boundaries are available for downloading.<\/jats:p>\n Availabililty: \u00a0<\/jats:p>\n Contact: \u00a0almz@umich.edu<\/jats:p>","DOI":"10.1093\/bioinformatics\/btk023","type":"journal-article","created":{"date-parts":[[2006,1,6]],"date-time":"2006-01-06T01:39:12Z","timestamp":1136511552000},"page":"623-625","source":"Crossref","is-referenced-by-count":1025,"title":["OPM: Orientations of Proteins in Membranes database"],"prefix":"10.1093","volume":"22","author":[{"given":"Mikhail A.","family":"Lomize","sequence":"first","affiliation":[{"name":"College of Literature, Science and the Arts, University of Michigan 1 \u00a0 1 \u00a0 \u00a0 Ann Arbor, MI 48109-1065, USA"}]},{"given":"Andrei L.","family":"Lomize","sequence":"additional","affiliation":[{"name":"College of Pharmacy, University of Michigan 2 \u00a0 2 \u00a0 \u00a0 Ann Arbor, MI 48109-1065, USA"}]},{"given":"Irina D.","family":"Pogozheva","sequence":"additional","affiliation":[{"name":"College of Pharmacy, University of Michigan 2 \u00a0 2 \u00a0 \u00a0 Ann Arbor, MI 48109-1065, USA"}]},{"given":"Henry I.","family":"Mosberg","sequence":"additional","affiliation":[{"name":"College of Pharmacy, University of Michigan 2 \u00a0 2 \u00a0 \u00a0 Ann Arbor, MI 48109-1065, USA"}]}],"member":"286","published-online":{"date-parts":[[2006,1,5]]},"reference":[{"key":"2023012408515535400_b1","doi-asserted-by":"crossref","first-page":"D226","DOI":"10.1093\/nar\/gkh039","article-title":"SCOP database in 2004: refinements integrate structure and sequence family data","volume":"32","author":"Andreeva","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"2023012408515535400_b2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1093-3263(03)00122-0","article-title":"Insertion of X-ray structures of proteins in membranes","volume":"22","author":"Basyn","year":"2003","journal-title":"J. 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