{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T00:45:39Z","timestamp":1740185139401,"version":"3.37.3"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"21","license":[{"start":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T00:00:00Z","timestamp":1663804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Symbiont","award":["ANR-17-CE40-0036","DFG-391322026"]},{"name":"Systems Biology Grant of the University of Surrey"},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["5R35GM119770"],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Horizon 2020","award":["826121","765158","813545"]},{"name":"NIH\/NIGMS","award":["R35GM141891"]},{"name":"DFG, German Research Foundation"},{"name":"Cluster of Excellence EXC 2124 Controlling Microbes to Fight Infections","award":["MIC ITMO 2020"]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01-AI134058"],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,31]]},"abstract":"Abstract<\/jats:title>\n \n Summary<\/jats:title>\n The Community of Special Interest (COSI) in Computational Modelling of Biological Systems (SysMod) brings together interdisciplinary scientists interested in combining data-driven computational modelling, multi-scale mechanistic frameworks, large-scale -omics data and bioinformatics. SysMod\u2019s main activity is an annual meeting at the Intelligent Systems for Molecular Biology (ISMB) conference, a meeting for computer scientists, biologists, mathematicians, engineers and computational and systems biologists. The 2021 SysMod meeting was conducted virtually due to the ongoing COVID-19 pandemic (coronavirus disease 2019). During the 2-day meeting, the development of computational tools, approaches and predictive models was discussed, along with their application to biological systems, emphasizing disease mechanisms. This report summarizes the meeting.<\/jats:p>\n <\/jats:sec>\n \n Availability and implementation<\/jats:title>\n All resources and further information are freely accessible at https:\/\/sysmod.info.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btac609","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T15:10:14Z","timestamp":1663859414000},"page":"4990-4993","source":"Crossref","is-referenced-by-count":1,"title":["Computational modelling in health and disease: highlights of the 6th annual SysMod meeting"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9687-7426","authenticated-orcid":false,"given":"Anna","family":"Niarakis","sequence":"first","affiliation":[{"name":"GenHotel, Department of Biology, Univ \u00c9vry, University of Paris-Saclay, Genopole , 91025 \u00c9vry, France"},{"name":"Lifeware Group, Inria Saclay-\u00eele de France , Palaiseau 91120, France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4479-4183","authenticated-orcid":false,"given":"Juilee","family":"Thakar","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry , Rochester, NY, USA"},{"name":"Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry , Rochester, NY, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5640-7422","authenticated-orcid":false,"given":"Matteo","family":"Barberis","sequence":"additional","affiliation":[{"name":"Systems Biology, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey , GU2 7XH Guildford, Surrey, UK"},{"name":"Centre for Mathematical and Computational Biology, CMCB, University of Surrey , GU2 7XH Guildford, Surrey, UK"},{"name":"Synthetic Systems Biology and Nuclear Organization, Swammerdam Institute for Life Sciences University of Amsterdam , 1098 XH Amsterdam, The Netherlands"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3766-4233","authenticated-orcid":false,"given":"Mar\u00eda","family":"Rodr\u00edguez Mart\u00ednez","sequence":"additional","affiliation":[{"name":"IBM Research Europe , Rueschlikon 8803, Switzerland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3653-1906","authenticated-orcid":false,"given":"Tom\u00e1\u0161","family":"Helikar","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Nebraska-Lincoln , Lincoln, NE68588-0664, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0341-0705","authenticated-orcid":false,"given":"Marc","family":"Birtwistle","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biomolecular Engineering, Clemson University , Clemson, SC 29634, USA"},{"name":"Department of Bioengineering, Clemson University , Clemson, SC 29634, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2350-0756","authenticated-orcid":false,"given":"Claudine","family":"Chaouiya","sequence":"additional","affiliation":[{"name":"Aix-Marseille Univ, CNRS, I2M , Marseille 13009, France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7835-1148","authenticated-orcid":false,"given":"Laurence","family":"Calzone","sequence":"additional","affiliation":[{"name":"Institut Curie, PSL Research University , Paris, France"},{"name":"INSERM, U900 , Paris, France"},{"name":"MINES ParisTech , Paris, France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1240-5553","authenticated-orcid":false,"given":"Andreas","family":"Dr\u00e4ger","sequence":"additional","affiliation":[{"name":"Computational Systems Biology of Infections and Antimicrobial-Resistant Pathogens, Institute for Bioinformatics and Medical Informatics (IBMI), Eberhard Karl University of T\u00fcbingen , 72076 T\u00fcbingen, Germany"},{"name":"Department of Computer Science, Eberhard Karl University of T\u00fcbingen , 72076 T\u00fcbingen, Germany"},{"name":"German Center for Infection Research (DZIF), Partner Site T\u00fcbingen , T\u00fcbingen 72076, Germany"},{"name":"Cluster of Excellence \u2018Controlling Microbes to Fight Infections,\u2019 Eberhard Karl University of T\u00fcbingen , T\u00fcbingen 72076, Germany"}]}],"member":"286","published-online":{"date-parts":[[2022,9,22]]},"reference":[{"key":"2022103112482495200_btac609-B1","doi-asserted-by":"crossref","first-page":"e1008874","DOI":"10.1371\/journal.pcbi.1008874","article-title":"Multicellular spatial model of RNA virus replication and interferon responses reveals factors controlling plaque growth dynamics","volume":"17","author":"Aponte-Serrano","year":"2021","journal-title":"PLoS Comput. 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