{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T11:51:56Z","timestamp":1744372316763,"version":"3.37.3"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"21","license":[{"start":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T00:00:00Z","timestamp":1622678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/T01959X\/1"],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"name":"FunPDBe","award":["BB\/P024351\/1"]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["104948"],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Molecular Biology Laboratory-European Bioinformatics Institute"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,5]]},"abstract":"Abstract<\/jats:title>\n \n Summary<\/jats:title>\n The PDBe aggregated API is an open-access and open-source RESTful API that provides programmatic access to a wealth of macromolecular structural data and their functional and biophysical annotations through 80+ API endpoints. The API is powered by the PDBe graph database (https:\/\/pdbe.org\/graph-schema), an open-access integrative knowledge graph that can be used as a discovery tool to answer complex biological questions.<\/jats:p>\n <\/jats:sec>\n \n Availability and implementation<\/jats:title>\n The PDBe aggregated API provides up-to-date access to the PDBe graph database, which has weekly releases with the latest data from the Protein Data Bank, integrated with updated annotations from UniProt, Pfam, CATH, SCOP and the PDBe-KB partner resources. The complete list of all the available API endpoints and their descriptions are available at https:\/\/pdbe.org\/graph-api. The source code of the Python 3.6+ API application is publicly available at https:\/\/gitlab.ebi.ac.uk\/pdbe-kb\/services\/pdbe-graph-api.<\/jats:p>\n <\/jats:sec>\n \n Supplementary information<\/jats:title>\n Supplementary data are available at Bioinformatics online.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btab424","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T20:46:40Z","timestamp":1622666800000},"page":"3950-3952","source":"Crossref","is-referenced-by-count":18,"title":["PDBe aggregated API: programmatic access to an integrative knowledge graph of molecular structure data"],"prefix":"10.1093","volume":"37","author":[{"given":"Sreenath","family":"Nair","sequence":"first","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"given":"Mih\u00e1ly","family":"V\u00e1radi","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"given":"Nurul","family":"Nadzirin","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6435-4719","authenticated-orcid":false,"given":"Luk\u00e1\u0161","family":"Pravda","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"given":"Stephen","family":"Anyango","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"given":"Saqib","family":"Mir","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"given":"John","family":"Berrisford","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"given":"David","family":"Armstrong","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"given":"Aleksandras","family":"Gutmanas","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8439-5964","authenticated-orcid":false,"given":"Sameer","family":"Velankar","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Protein Data Bank in Europe, Wellcome Genome Campus , Hinxton CB10 1SA, UK"}]}],"member":"286","published-online":{"date-parts":[[2021,6,3]]},"reference":[{"key":"2023051607343412700_btab424-B1","first-page":"D335","article-title":"PDBe: improved findability of macromolecular structure data in the PDB","volume":"48","author":"Armstrong","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"2023051607343412700_btab424-B2","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.3390\/ijms20112783","article-title":"A structure-based drug discovery paradigm","volume":"20","author":"Batool","year":"2019","journal-title":"Int. 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