{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T21:11:01Z","timestamp":1723324261376},"reference-count":8,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"vor","delay-in-days":60,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["U54MD007598"],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["S21MD000103"],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["UL1TR001881"],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Appl Clin Inform"],"published-print":{"date-parts":[[2021,5]]},"abstract":"Abstract<\/jats:title>\n Objectives\u2003This article presents a comparative study of two Health Level Seven International (HL7) standards for clinical knowledge representation, the Arden Syntax and the Clinical Quality Language (CQL), regarding their expressiveness and utility to represent knowledge for clinical decision support (CDS) systems.<\/jats:p>\n Methods\u2003We compiled a concatenated set of features from both languages and made descriptive comparisons of 27 categories covering areas of language characteristics, data, control statements, and operators.<\/jats:p>\n Results\u2003Both Arden and CQL have similar constructs that can be used for representing CDS knowledge but also have unique constructs that could support distinct use cases. They have constructs that fully or partially address several of the categories used in the comparison, except for data models and terminologies in Arden and event triggering and iteration statements in CQL.<\/jats:p>\n Conclusion\u2003These standards can facilitate the sharing, management, and reuse of computable knowledge, and permit knowledge to be represented with their languages and converted to a machine-friendly executable code that can be shared and reused by other systems. Having support for standard data models and terminologies will continue to be a differential for adoption of a language. The HL7 working groups responsible for developing these standards can direct future development to enhance the functions of the standard and address the gaps identified in this study.<\/jats:p>","DOI":"10.1055\/s-0041-1731001","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T23:10:52Z","timestamp":1625094652000},"page":"495-506","source":"Crossref","is-referenced-by-count":8,"title":["A Comparison of Arden Syntax and Clinical Quality Language as Knowledge Representation Formalisms for Clinical Decision Support"],"prefix":"10.1055","volume":"12","author":[{"given":"Andrey","family":"Soares","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Colorado, Aurora, Colorado, United States"}]},{"given":"Robert A.","family":"Jenders","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, Los Angeles, California, United States"}]},{"given":"Robert","family":"Harrison","sequence":"additional","affiliation":[{"name":"University of Colorado Health (UCHealth), Aurora, Colorado, United States"}]},{"given":"Lisa M.","family":"Schilling","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Colorado, Aurora, Colorado, United States"}]}],"member":"194","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1056\/NEJMp1006114","article-title":"The \u201cmeaningful use\u201d regulation for electronic health records","volume":"363","author":"D Blumenthal","year":"2010","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.artmed.2016.08.001","article-title":"Evolution of the Arden Syntax: key technical issues from the standards development organization perspective","volume":"92","author":"R A Jenders","year":"2018","journal-title":"Artif Intell Med"},{"issue":"01","key":"ref10","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1055\/s-0040-1701253","article-title":"To Share is Human! Advancing evidence into practice through a national repository of interoperable clinical decision support","volume":"11","author":"E A Lomotan","year":"2020","journal-title":"Appl Clin Inform"},{"key":"ref11","first-page":"417","volume-title":"Chapter 15 - Decision rules and expressions","author":"R A Jenders","year":"2014","edition":"2nd ed."},{"key":"ref12","volume-title":"Sebesta. Concepts of Programming Languages","author":"W Robert","year":"2013","edition":"10th ed."},{"issue":"04","key":"ref17","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1136\/amiajnl-2011-000512","article-title":"Executing medical logic modules expressed in ArdenML using Drools","volume":"19","author":"C Y Jung","year":"2012","journal-title":"J Am Med Inform Assoc"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.artmed.2015.09.009","article-title":"Using Arden Syntax for the creation of a multi-patient surveillance dashboard","volume":"92","author":"S Kraus","year":"2018","journal-title":"Artif Intell Med"},{"issue":"04","key":"ref22","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1006\/cbmr.1994.1023","article-title":"Rationale for the Arden Syntax","volume":"27","author":"G Hripcsak","year":"1994","journal-title":"Comput Biomed Res"}],"container-title":["Applied Clinical Informatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1731001.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T23:10:58Z","timestamp":1625094658000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1731001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":8,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2021,5,26]]},"published-print":{"date-parts":[[2021,5]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1731001","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1869-0327"],"issn-type":[{"value":"1869-0327","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}