{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:51:07Z","timestamp":1740142267900,"version":"3.37.3"},"reference-count":16,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2020,10,26]]},"DOI":"10.1021\/acs.jcim.0c01146","type":"journal-article","created":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T18:11:51Z","timestamp":1602699111000},"page":"4421-4423","source":"Crossref","is-referenced-by-count":18,"title":["Ligand Entropy Is Hard but Should Not Be Ignored"],"prefix":"10.1021","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7301-6076","authenticated-orcid":true,"given":"David A.","family":"Winkler","sequence":"first","affiliation":[{"name":"La Trobe University, Kingsbury Drive, Bundoora 3042, Australia"},{"name":"Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Australia"},{"name":"School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom"},{"name":"CSIRO Data61, Pullenvale 4069, Australia"}]}],"member":"316","published-online":{"date-parts":[[2020,10,14]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-0917-9"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.9b07593"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/C5SC02678D"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.0c00057"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2015.1032936"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1039\/C7CP07623A"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/bip.20983"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0610494104"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-083012-130318"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/ci9002987"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01089"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21334"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/wcms.1465"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.0c00411"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b02682"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0134(2000)41:4+<93::AID-PROT90>3.0.CO;2-0"}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.0c01146","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T16:55:17Z","timestamp":1682614517000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jcim.0c01146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,14]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10,26]]}},"alternative-id":["10.1021\/acs.jcim.0c01146"],"URL":"https:\/\/doi.org\/10.1021\/acs.jcim.0c01146","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"type":"print","value":"1549-9596"},{"type":"electronic","value":"1549-960X"}],"subject":[],"published":{"date-parts":[[2020,10,14]]}}}