{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T04:40:34Z","timestamp":1726029634853},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["AG052062, EB020843, and GM098308"],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"crossref","award":["15SDG25960005"],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.neuroimage.2017.01.049","type":"journal-article","created":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T10:17:03Z","timestamp":1484907423000},"page":"77-87","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":133,"special_numbering":"C","title":["Functional and oxygen-metabolic photoacoustic microscopy of the awake mouse brain"],"prefix":"10.1016","volume":"150","author":[{"given":"Rui","family":"Cao","sequence":"first","affiliation":[]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[]},{"given":"Bo","family":"Ning","sequence":"additional","affiliation":[]},{"given":"Naidi","family":"Sun","sequence":"additional","affiliation":[]},{"given":"Tianxiong","family":"Wang","sequence":"additional","affiliation":[]},{"given":"Zhiyi","family":"Zuo","sequence":"additional","affiliation":[]},{"given":"Song","family":"Hu","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/j.neuroimage.2017.01.049_bib1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/bja\/aet059","article-title":"Pharmacological perioperative brain neuroprotection: a qualitative review of randomized clinical trials","volume":"110","author":"Bilotta","year":"2013","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib2","doi-asserted-by":"crossref","first-page":"4017","DOI":"10.1364\/OL.36.004017","article-title":"In vivo flow speed measurement of capillaries by photoacoustic correlation spectroscopy","volume":"36","author":"Chen","year":"2011","journal-title":"Opt. Lett."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib3","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1038\/nprot.2012.106","article-title":"LOTOS-based two-photon calcium imaging of dendritic spines in vivo","volume":"7","author":"Chen","year":"2012","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib4","doi-asserted-by":"crossref","first-page":"3941","DOI":"10.1364\/BOE.6.003941","article-title":"Cerebral metabolic rate of oxygen (CMRO_2) assessed by combined Doppler and spectroscopic OCT","volume":"6","author":"Chong","year":"2015","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3389\/fnana.2011.00029","article-title":"The evolution of the brain, the human nature of cortical circuits, and intellectual creativity","volume":"5","author":"DeFelipe","year":"2011","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib6","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1038\/nn.2648","article-title":"Functional imaging of hippocampal place cells at cellular resolution during virtual navigation","volume":"13","author":"Dombeck","year":"2010","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib7","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.neuron.2007.08.003","article-title":"Imaging large-scale neural activity with cellular resolution in awake, mobile mice","volume":"56","author":"Dombeck","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib8","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1038\/nmeth.1530","article-title":"Chronic optical access through a polished and reinforced thinned skull","volume":"7","author":"Drew","year":"2010","journal-title":"Nat. Methods"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib9","series-title":"The Laboratory Mouse, The Laboratory Mouse","author":"Everds","year":"2004"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib10","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1038\/nmeth.1256","article-title":"High-speed, miniaturized fluorescence microscopy in freely moving mice","volume":"5","author":"Flusberg","year":"2008","journal-title":"Nat. Methods"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib11","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1073\/pnas.83.4.1140","article-title":"Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects","volume":"83","author":"Fox","year":"1986","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib12","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/j.neuroimage.2010.03.060","article-title":"The effect of different anesthetics on neurovascular coupling","volume":"51","author":"Franceschini","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib13","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/nn.2140","article-title":"Population imaging of ongoing neuronal activity in the visual cortex of awake rats","volume":"11","author":"Greenberg","year":"2008","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib14","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.neuron.2015.03.055","article-title":"Cellular Level Brain Imaging in Behaving Mammals: an Engineering Approach","volume":"86","author":"Hamel","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib15","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/nature08499","article-title":"Intracellular dynamics of hippocampal place cells during virtual navigation","volume":"461","author":"Harvey","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib16","doi-asserted-by":"crossref","unstructured":"Hedenstierna, G., Rothen, H.U., 2012. Respiratory function during anesthesia: effects on gas exchange In: Comprehensive Physiology. John Wiley & Sons, Inc., Hoboken, NJ, USA. doi:10.1002\/cphy.c080111.","DOI":"10.1002\/cphy.c080111"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib17","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0896-6273(01)00421-4","article-title":"A miniature head-mounted two-photon microscope","volume":"31","author":"Helmchen","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib18","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0896-6273(01)00421-4","article-title":"A miniature head-mounted two-photon microscope. high-resolution brain imaging in freely moving animals","volume":"31","author":"Helmchen","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib19","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/jcbfm.1994.62","article-title":"Role of nitric oxide in regulating cerebrocortical oxygen consumption and blood flow during hypercapnia","volume":"14","author":"Horvath","year":"1994","journal-title":"J. Cereb. blood Flow. Metab."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1109\/JQE.2016.2569458","article-title":"Listening to the brain with photoacoustics","volume":"22","author":"Hu","year":"2016","journal-title":"IEEE J. Sel. Top. Quantum Electron"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib21","first-page":"10","article-title":"Neurovascular photoacoustic tomography","volume":"2","author":"Hu","year":"2010","journal-title":"Front. Neuroenergetics"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib22","doi-asserted-by":"crossref","first-page":"110503","DOI":"10.1117\/1.JBO.17.11.110503","article-title":"Photoacoustic detection of functional responses in the motor cortex of awake behaving monkey during forelimb movement","volume":"17","author":"Jo","year":"2012","journal-title":"J. Biomed. Opt."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib23","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1097\/00000542-200309000-00015","article-title":"Effects of sevoflurane, propofol and adjunct nitrous oxide on regional cerebral blood flow, oxygen consumption, and blood volume in humans","volume":"99","author":"Kaisti","year":"2003","journal-title":"Anesthesiology"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib24","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1097\/00000542-200206000-00015","article-title":"Effects of surgical levels of propofol and sevoflurane anesthesia on cerebral blood flow in healthy subjects studied with positron emission tomography","volume":"96","author":"Kaisti","year":"2002","journal-title":"J. Am. Soc. Anesthesiol."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib25","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1038\/sj.jcbfm.9600410","article-title":"Inhalational anesthetics as neuroprotectants or chemical preconditioning agents in ischemic brain","volume":"27","author":"Kitano","year":"2007","journal-title":"J. Cereb. Blood Flow. Metab."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.0030355","article-title":"From art to engineering? The rise of in vivo mammalian electrophysiology via genetically targeted labeling and nonlinear imaging","author":"Kleinfeld","year":"2005","journal-title":"PLoS Biol."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib27","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.neuroimage.2006.02.021","article-title":"Investigating neural\u2013hemodynamic coupling and the hemodynamic response function in the awake rat","volume":"32","author":"Martin","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib28","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1038\/jcbfm.2012.50","article-title":"Anesthesia and the quantitative evaluation of neurovascular coupling","volume":"32","author":"Masamoto","year":"2012","journal-title":"J. Cereb. Blood Flow. Metab."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib29","doi-asserted-by":"crossref","first-page":"7593","DOI":"10.1073\/pnas.121179898","article-title":"Effects of anesthesia on functional activation of cerebral blood flow and metabolism","volume":"98","author":"Nakao","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib30","first-page":"1","article-title":"Ultrasound-aided multi-parametric photoacoustic microscopy of the mouse brain","author":"Ning","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib31","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1002\/mrm.21759","article-title":"Anesthetic effects on regional CBF, BOLD, and the coupling between task-induced changes in CBF and BOLD: an fMRI study in normal human subjects","volume":"60","author":"Qiu","year":"2008","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib32","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1097\/00000542-198711000-00020","article-title":"Anesthetic depression of myocardial contractility: a review of possible mechanisms","volume":"67","author":"Rusy","year":"1987","journal-title":"Anesthesiology"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib33","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/nmeth.1490","article-title":"Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue","volume":"7","author":"Sakadzi\u0107","year":"2010","journal-title":"Nat. Methods"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib34","doi-asserted-by":"crossref","first-page":"19557","DOI":"10.1073\/pnas.0903680106","article-title":"Visually evoked activity in cortical cells imaged in freely moving animals","volume":"106","author":"Sawinski","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib35","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.neuron.2013.08.002","article-title":"Cellular resolution functional imaging in behaving rats using voluntary head restraint","volume":"80","author":"Scott","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib36","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1038\/jcbfm.2008.166","article-title":"Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke","volume":"29","author":"Shih","year":"2009","journal-title":"J. Cereb. Blood Flow. Metab."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib37","doi-asserted-by":"crossref","first-page":"8111","DOI":"10.1523\/JNEUROSCI.20-21-08111.2000","article-title":"Long-term optical imaging and spectroscopy reveal mechanisms underlying the intrinsic signal and stability of cortical maps in V1 of behaving monkeys","volume":"20","author":"Shtoyerman","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib38","first-page":"822345","article-title":"Vessel segmentation analysis of ischemic stroke images acquired with photoacoustic microscopy","volume":"8223","author":"Soetikno","year":"2012","journal-title":"SPIE BIOS"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib39","doi-asserted-by":"crossref","first-page":"7319","DOI":"10.1073\/pnas.1232232100","article-title":"In vivo two-photon calcium imaging of neuronal networks","volume":"100","author":"Stosiek","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib40","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/00000542-197701000-00007","article-title":"The nonlinear responses of cerebral metabolism to low concentrations of halothane, enflurane, isoflurane, and thiopental","volume":"46","author":"Stullken","year":"1977","journal-title":"Anesthesiology"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib41","article-title":"Wearable scanning photoacoustic brain imaging in behaving rats","volume":"6","author":"Tang","year":"2016","journal-title":"J. Biophotonics"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib42","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1177\/0271678X15606460","article-title":"Acute hypoxia increases the cerebral metabolic rate - a magnetic resonance imaging study","volume":"36","author":"Vestergaard","year":"2016","journal-title":"J. Cereb. Blood Flow. Metab."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib43","doi-asserted-by":"crossref","first-page":"45006","DOI":"10.1117\/1.NPh.3.4.045006","article-title":"Multiparametric photoacoustic microscopy of the mouse brain with 300-kHz A-line rate","volume":"3","author":"Wang","year":"2016","journal-title":"Neurophotonics"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib44","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1126\/science.1216210","article-title":"Photoacoustic tomography: in vivo imaging from organelles to organs","volume":"335","author":"Wang","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib45","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1038\/jcbfm.2011.32","article-title":"Cerebral metabolic rate in hypercapnia: controversy continues","volume":"31","author":"Yablonskiy","year":"2011","journal-title":"J. Cereb. Blood Flow. Metab."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib46","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nprot.2009.222","article-title":"Thinned-skull cranial window technique for long-term imaging of the cortex in live mice","volume":"5","author":"Yang","year":"2010","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib47","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/nmeth.3336","article-title":"High-speed label-free functional photoacoustic microscopy of mouse brain in action","volume":"12","author":"Yao","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib48","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1364\/BOE.5.003603","article-title":"In vivo functional microangiography by visible-light optical coherence tomography","volume":"5","author":"Yi","year":"2014","journal-title":"Biomed. Opt. Express"},{"key":"10.1016\/j.neuroimage.2017.01.049_bib49","doi-asserted-by":"crossref","first-page":"5706","DOI":"10.2174\/1381612820666140204120829","article-title":"Anesthetic cardioprotection in clinical practice from proof-of-concept to clinical applications","volume":"20","author":"Zaugg","year":"2014","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib50","doi-asserted-by":"crossref","first-page":"53901","DOI":"10.1063\/1.2435697","article-title":"Imaging of hemoglobin oxygen saturation variations in single vessels in vivo using photoacoustic microscopy","volume":"90","author":"Zhang","year":"2007","journal-title":"Appl. Phys. Lett."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib51","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/2045-9912-2-10","article-title":"Are volatile anesthetics neuroprotective or neurotoxic?","volume":"2","author":"Zuo","year":"2012","journal-title":"Med. Gas. Res."},{"key":"10.1016\/j.neuroimage.2017.01.049_bib52","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1097\/ACO.0000000000000212","article-title":"Update on anesthetic neuroprotection","volume":"28","author":"Zwerus","year":"2015","journal-title":"Curr. Opin. Anaesthesiol."}],"container-title":["NeuroImage"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811917300587?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053811917300587?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T23:09:22Z","timestamp":1609196962000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053811917300587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":52,"alternative-id":["S1053811917300587"],"URL":"https:\/\/doi.org\/10.1016\/j.neuroimage.2017.01.049","relation":{},"ISSN":["1053-8119"],"issn-type":[{"value":"1053-8119","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functional and oxygen-metabolic photoacoustic microscopy of the awake mouse brain","name":"articletitle","label":"Article Title"},{"value":"NeuroImage","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.neuroimage.2017.01.049","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}