{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T20:29:37Z","timestamp":1721939377057},"reference-count":81,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["DE180101138","DE210101549"],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Computers in Biology and Medicine"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.compbiomed.2021.105150","type":"journal-article","created":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T02:02:05Z","timestamp":1639706525000},"page":"105150","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Detailed comparison of anatomy and airflow dynamics in human and cynomolgus monkey nasal cavity"],"prefix":"10.1016","volume":"141","author":[{"ORCID":"http:\/\/orcid.org\/0000-0002-7779-1926","authenticated-orcid":false,"given":"Lin","family":"Tian","sequence":"first","affiliation":[]},{"ORCID":"http:\/\/orcid.org\/0000-0002-2812-6188","authenticated-orcid":false,"given":"Jingliang","family":"Dong","sequence":"additional","affiliation":[]},{"given":"Yidan","family":"Shang","sequence":"additional","affiliation":[]},{"given":"Jiyuan","family":"Tu","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"issue":"7869","key":"10.1016\/j.compbiomed.2021.105150_bib1","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/d41586-021-01894-z","article-title":"The US is boosting funding for research monkeys in the wake of COVID","volume":"595","author":"Subbaraman","year":"2021","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.compbiomed.2021.105150_bib2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1089\/jamp.2018.1505","article-title":"Deposition of aerosolized lucinactant in nonhuman primates","volume":"33","author":"Gregory","year":"2020","journal-title":"J. Aerosol Med. Pulm. Drug Deliv."},{"issue":"11","key":"10.1016\/j.compbiomed.2021.105150_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008949","article-title":"Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: a nonhuman primate model of COVID-19 progression","volume":"16","author":"Zheng","year":"2020","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.compbiomed.2021.105150_bib4","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s12985-020-01396-w","article-title":"Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase","volume":"17","author":"Cross","year":"2020","journal-title":"Virol. J."},{"issue":"8","key":"10.1016\/j.compbiomed.2021.105150_bib5","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1097\/01.LAB.0000080599.43791.01","article-title":"Pathology of inhalation anthrax in cynomolgus monkeys (Macaca fascicularis)","volume":"83","author":"Vasconcelos","year":"2003","journal-title":"Lab. Invest."},{"issue":"2","key":"10.1016\/j.compbiomed.2021.105150_bib6","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1093\/ilar\/ilx030","article-title":"Nonhuman primate models of respiratory disease: past, present, and future","volume":"58","author":"Miller","year":"2017","journal-title":"ILAR J."},{"issue":"6","key":"10.1016\/j.compbiomed.2021.105150_bib7","first-page":"924","article-title":"Respiratory responses in subhuman primates with immediate type hypersensitivity","volume":"73","author":"Patterson","year":"1969","journal-title":"J. Lab. Clin. Med."},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib8","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1152\/japplphysiol.00162.2011","article-title":"Bronchoconstriction in nonhuman primates: a species comparison","volume":"111","author":"Seehase","year":"2011","journal-title":"J. Appl. Physiol."},{"issue":"4","key":"10.1016\/j.compbiomed.2021.105150_bib9","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1152\/jappl.1981.50.4.754","article-title":"Bronchial reactivity to inhaled methacholine in cigarette-smoking baboons","volume":"50","author":"Roehrs","year":"1981","journal-title":"J. Appl. Physiol."},{"issue":"4","key":"10.1016\/j.compbiomed.2021.105150_bib10","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1038\/nm0496-430","article-title":"The Philippine cynomolgus monkey (Macaca fasicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease","volume":"2","author":"Walsh","year":"1996","journal-title":"Nat. Med."},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib11","first-page":"315","article-title":"Nonhuman primate models of measles","volume":"46","author":"Kobune","year":"1996","journal-title":"Lab. Anim. Sci."},{"key":"10.1016\/j.compbiomed.2021.105150_bib12","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.antiviral.2015.02.011","article-title":"The use of nonhuman primates in research on seasonal, pandemic and avian influenza","volume":"117","author":"Davis","year":"2015","journal-title":"Antivir. Res."},{"issue":"2","key":"10.1016\/j.compbiomed.2021.105150_bib13","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1034\/j.1600-0684.2002.01006.x","article-title":"A rhesus monkey model of respiratory syncytial virus infection","volume":"31","author":"McArthur-Vaughan","year":"2002","journal-title":"J. Med. Primatol."},{"issue":"20","key":"10.1016\/j.compbiomed.2021.105150_bib14","doi-asserted-by":"crossref","first-page":"11401","DOI":"10.1128\/JVI.78.20.11401-11404.2004","article-title":"Macaque model for severe acute respiratory syndrome","volume":"78","author":"Rowe","year":"2004","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.compbiomed.2021.105150_bib15","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/infdis\/jit590","article-title":"An animal model of MERS produced by infection of rhesus macaques with MERS coronavirus","volume":"209","author":"Yao","year":"2014","journal-title":"J. Infect. Dis."},{"issue":"8","key":"10.1016\/j.compbiomed.2021.105150_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004250","article-title":"Infection with MERS-CoV causes lethal pneumonia in the common marmoset","volume":"10","author":"Falzarano","year":"2014","journal-title":"PLoS Pathog."},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib17","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/0272-0590(87)90037-6","article-title":"One-year inhalation toxicity study of chlorine in rhesus monkeys (Macaca mulatta)","volume":"9","author":"Klonne","year":"1987","journal-title":"Fund. Appl. Toxicol."},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib18","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0041-008X(83)90276-4","article-title":"A 26-week inhalation toxicity study with formaldehyde in the monkey, rat, and hamster","volume":"68","author":"Rusch","year":"1983","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"121","key":"10.1016\/j.compbiomed.2021.105150_bib19","first-page":"1","article-title":"Sub-chronic inhalation of high concentrations of manganese sulfate induces lower airway pathology in rhesus monkeys","volume":"6","author":"Dorman","year":"2005","journal-title":"Respir. Res."},{"issue":"5\u20136","key":"10.1016\/j.compbiomed.2021.105150_bib20","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1080\/15287398209530201","article-title":"Effects of inhalation exposure to hexachlorocyclopentadiene on rats and monkeys","volume":"9","author":"Rand","year":"1982","journal-title":"J. Toxicol. Environ. Health"},{"issue":"1","key":"10.1016\/j.compbiomed.2021.105150_bib21","first-page":"52","article-title":"Tests for the chronic toxicity of propylene glycol and triethylene glycol on monkeys and rats by vapor inhalation and oral administration","volume":"91","author":"Robertson","year":"1947","journal-title":"J. Pharmacol. Exp. Therapeut."},{"issue":"123","key":"10.1016\/j.compbiomed.2021.105150_bib22","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.addr.2017.10.005","article-title":"Animal models of smoke inhalation injury and related acute and chronic lung diseases","volume":"1","author":"Reczy\u0144ska","year":"2018","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib23","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/ajim.4700110312","article-title":"Two-year inhalation toxicity study of petroleum coke in rats and monkeys","volume":"11","author":"Klonne","year":"1987","journal-title":"Am. J. Ind. Med."},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib24","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/00004032-197309000-00003","article-title":"A five-year inhalation study with natural uranium dioxide (UO2) dust. II. Postexposure retention and biologic effects in the monkey, dog and rat","volume":"25","author":"Leach","year":"1973","journal-title":"Health Phys."},{"issue":"6","key":"10.1016\/j.compbiomed.2021.105150_bib25","doi-asserted-by":"crossref","first-page":"545","DOI":"10.3109\/10915818609141025","article-title":"Chronic inhalation toxicity of fibrous glass in rats and monkeys","volume":"5","author":"Mitchell","year":"1986","journal-title":"J. Am. Coll. Toxicol."},{"issue":"4","key":"10.1016\/j.compbiomed.2021.105150_bib26","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1089\/jam.1997.10.319","article-title":"A comparative analysis of primate nasal airways using magnetic resonance imaging and nasal casts","volume":"10","author":"Yeh","year":"1997","journal-title":"J. Aerosol Med."},{"issue":"14","key":"10.1016\/j.compbiomed.2021.105150_bib27","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1080\/08958370500241270","article-title":"Inertial particle deposition in a monkey nasal mold compared with that in human nasal replicas","volume":"17","author":"Kelly","year":"2005","journal-title":"Inhal. Toxicol."},{"issue":"11\u201312","key":"10.1016\/j.compbiomed.2021.105150_bib28","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1080\/08958378.2018.1545810","article-title":"Particle and inhalation exposure in human and monkey computational airway models","volume":"30","author":"Phuong","year":"2018","journal-title":"Inhal. Toxicol."},{"issue":"1","key":"10.1016\/j.compbiomed.2021.105150_bib29","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/ar.1092150107","article-title":"A morphometric comparison of the nasopharyngeal airway of laboratory animals and humans","volume":"215","author":"Patra","year":"1986","journal-title":"Anat. Rec."},{"issue":"12","key":"10.1016\/j.compbiomed.2021.105150_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/pharmaceutics12121227","article-title":"Brain and nasal cavity anatomy of the cynomolgus monkey: species differences from the viewpoint of direct delivery from the nose to the brain","volume":"12","author":"Sakane","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.compbiomed.2021.105150_bib31","first-page":"321","article-title":"From CT scans to CFD modelling\u2014fluid and heat transfer in a realistic human nasal cavity","volume":"3","author":"Inthavong","year":"2009","journal-title":"Eng Appl Comp Fluid"},{"key":"10.1016\/j.compbiomed.2021.105150_bib32","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jaerosci.2017.08.006","article-title":"Human nasal olfactory deposition of inhaled nanoparticles at low to moderate breathing rate","volume":"113","author":"Tian","year":"2017","journal-title":"J. Aerosol Sci."},{"issue":"6","key":"10.1016\/j.compbiomed.2021.105150_bib33","first-page":"1","article-title":"Correlation of regional deposition dosage for inhaled nanoparticles in human and rat olfactory","volume":"16","author":"Tian","year":"2019","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cnm.3414","article-title":"Numerical analysis of nanoparticle transport and deposition in a cynomolgus monkey nasal passage","volume":"37","author":"Dong","year":"2021","journal-title":"International Journal for Numerical Methods in Biomedical Engineering"},{"issue":"1","key":"10.1016\/j.compbiomed.2021.105150_bib35","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1080\/01926230601072343","article-title":"Three-dimensional mapping of ozone-induced injury in the nasal airways of monkeys using magnetic resonance imaging and morphometric techniques","volume":"35","author":"Carey","year":"2007","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib36","volume":"vol. 66","year":"1994"},{"issue":"4","key":"10.1016\/j.compbiomed.2021.105150_bib37","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/1099-1263(200007\/08)20:4<273::AID-JAT657>3.0.CO;2-X","article-title":"Allometric respiration\/body mass data for animals to be used for estimates of inhalation toxicity to young adult humans","volume":"20","author":"Bide","year":"2000","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib38","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.resp.2008.01.012","article-title":"Numerical simulations for detailed airflow dynamics in human nasal cavity","volume":"161","author":"Wen","year":"2008","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib39","series-title":"Nasal Physiology and Pathophysiology of Nasal Disorders","article-title":"Physiology: rhinomanometry","author":"Pallanch","year":"2013"},{"key":"10.1016\/j.compbiomed.2021.105150_bib40","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1152\/jappl.2000.89.1.323","article-title":"Detailed flow patterns in the nasal cavity","volume":"89","author":"Kelly","year":"2000","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib41","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1007\/s00405-003-0675-y","article-title":"Numerical simulation of airflow in the human nose","volume":"261","author":"Weinhold","year":"2004","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib42","series-title":"Head and Neck Surgery: Otolaryngology","year":"1998"},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib43","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jbiomech.2016.01.009","article-title":"A computational analysis of nasal vestibule morphologic variabilities on nasal function","volume":"49","author":"Ramprasad","year":"2016","journal-title":"J. Biomech."},{"issue":"20","key":"10.1016\/j.compbiomed.2021.105150_bib44","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1080\/00984100290071630","article-title":"Olfactory transport: a direct route of delivery of inhaled manganese phosphate to the rat brain","volume":"65","author":"Dorman","year":"2002","journal-title":"J. Toxicol. Environ. Health"},{"issue":"4","key":"10.1016\/j.compbiomed.2021.105150_bib45","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s00401-014-1261-7","article-title":"Olfactory bulb involvement in neurodegenerative diseases","volume":"127","author":"Attems","year":"2014","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib46","doi-asserted-by":"crossref","first-page":"100322","DOI":"10.1016\/j.impact.2021.100322","article-title":"Quantification of long-term accumulation of inhaled ultrafine particles via human olfactory-brain pathway due to environmental emissions \u2013 a pilot study","volume":"22","author":"Shang","year":"2021","journal-title":"Nanoimpact"},{"issue":"12","key":"10.1016\/j.compbiomed.2021.105150_bib47","doi-asserted-by":"crossref","first-page":"5790","DOI":"10.1128\/IAI.00520-08","article-title":"Identification of a surrogate marker for infection in the African green monkey model of inhalation anthrax","volume":"76","author":"Rossi","year":"2008","journal-title":"Infect. Immun."},{"issue":"10","key":"10.1016\/j.compbiomed.2021.105150_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0162918","article-title":"Measuring and characterizing the human nasal cycle","volume":"11","author":"Kahana-Zweig","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib49","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0021-8502(94)00113-D","article-title":"Physiologically realistic models of bronchial airway bifurcations","volume":"26","author":"Heistracher","year":"1995","journal-title":"J. Aerosol Sci."},{"issue":"2","key":"10.1016\/j.compbiomed.2021.105150_bib50","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1260\/1757-482X.4.2.159","article-title":"Transport and deposition of micro-and nano-particles in human tracheobronchial tree by an asymmetric multi-level bifurcation model","volume":"4","author":"Tian","year":"2012","journal-title":"J. Comput. Multiph. Flows"},{"key":"10.1016\/j.compbiomed.2021.105150_bib51","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1080\/02786820600660903","article-title":"Airflow and deposition of nanoparticles in a human nasal cavity","volume":"40","author":"Zamankhan","year":"2006","journal-title":"Aerosol. Sci. Technol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib52","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0021-8502(01)00168-9","article-title":"Inhalability of large solid particles","volume":"33","author":"Kennedy","year":"2002","journal-title":"J. Aerosol Sci."},{"issue":"2","key":"10.1016\/j.compbiomed.2021.105150_bib53","first-page":"157","article-title":"CFD model for a 3-D inhaling mannequin: verification and validation","volume":"50","author":"Anthony","year":"2006","journal-title":"Ann. Occup. Hyg."},{"key":"10.1016\/j.compbiomed.2021.105150_bib54","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.atmosenv.2012.07.071","article-title":"Detailed predictions of particle aspiration affected by respiratory inhalation and airflow","volume":"62","author":"Inthavong","year":"2012","journal-title":"Atmos. Environ."},{"issue":"4","key":"10.1016\/j.compbiomed.2021.105150_bib55","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3109\/08958370903295204","article-title":"Inhalability of micron particles through the nose and mouth","volume":"22","author":"Se","year":"2010","journal-title":"Inhal. Toxicol."},{"issue":"5","key":"10.1016\/j.compbiomed.2021.105150_bib56","doi-asserted-by":"crossref","first-page":"280","DOI":"10.3109\/08958378.2013.781250","article-title":"Source and trajectories of inhaled particles from a surrounding environment and its deposition in the respiratory airway","volume":"25","author":"Inthavong","year":"2013","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.compbiomed.2021.105150_bib57","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.compbiomed.2014.06.007","article-title":"Numerical investigation of regional particle deposition in the upper airway of a standing male mannequin in calm air surroundings","volume":"52","author":"Naseri","year":"2014","journal-title":"Comput. Biol. Med."},{"issue":"4","key":"10.1016\/j.compbiomed.2021.105150_bib58","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1089\/jam.1996.9.513","article-title":"Three-dimensional fluid particle trajectories in the human larynx and trachea","volume":"9","author":"Katz","year":"1996","journal-title":"J. Aerosol Med."},{"key":"10.1016\/j.compbiomed.2021.105150_bib59","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1089\/08942680152007864","article-title":"Effect of particle inlet distributions on deposition in a triple bifurcation lung airway model","volume":"14","author":"Zhang","year":"2010","journal-title":"J. Aerosol Med."},{"issue":"12","key":"10.1016\/j.compbiomed.2021.105150_bib60","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1080\/02786820300898","article-title":"Inspiratory deposition efficiency of ultrafine particles in a human airway bifurcation model","volume":"37","author":"Hofmann","year":"2003","journal-title":"Aerosol. Sci. Technol."},{"issue":"2","key":"10.1016\/j.compbiomed.2021.105150_bib61","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1260\/1757-482X.4.2.159","article-title":"Transport and deposition of micro-and nano-particles in human tracheobronchial tree by an asymmetric multi-level bifurcation model","volume":"4","author":"Tian","year":"2012","journal-title":"J. Comput. Multiph. Flows"},{"key":"10.1016\/j.compbiomed.2021.105150_bib62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaerosci.2013.02.001","article-title":"Fiber transport and deposition in human upper tracheobroncial airways","volume":"60","author":"Tian","year":"2013","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.compbiomed.2021.105150_bib63","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.4209\/aaqr.2018.09.0343","article-title":"Inhalation health risk assessment of human tracheobronchial tree under PM exposure in a bus stop scene","volume":"19","author":"Xu","year":"2019","journal-title":"Aerosol Air Qual. Res."},{"issue":"11","key":"10.1016\/j.compbiomed.2021.105150_bib64","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.4209\/aaqr.2020.01.0015","article-title":"A combined computational and experimental study on nanoparticle transport and partition in human trachea and upper Bronchi airways","volume":"20","author":"Ma","year":"2020","journal-title":"Aerosol Air Qual. Res."},{"key":"10.1016\/j.compbiomed.2021.105150_bib65","first-page":"1","article-title":"Transport and deposition of ultrafine particles in the upper tracheobronchial tree: a comparative study between approximate and realistic respiratory tract models","volume":"7","author":"Dong","year":"2021","journal-title":"Comput. Methods Biomech. Biomed. Eng."},{"issue":"2","key":"10.1016\/j.compbiomed.2021.105150_bib66","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1080\/089583798197772","article-title":"Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx","volume":"10","author":"Subramaniam","year":"1998","journal-title":"Inhal. Toxicol."},{"issue":"11","key":"10.1016\/j.compbiomed.2021.105150_bib67","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1080\/02786820300932","article-title":"Simulation of particle deposition in an idealized mouth with different small diameter inlets","volume":"37","author":"Matida","year":"2003","journal-title":"Aerosol. Sci. Technol."},{"issue":"1","key":"10.1016\/j.compbiomed.2021.105150_bib68","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.compfluid.2011.08.013","article-title":"Micron particle deposition in the nasal cavity using the v2\u2013f model","volume":"51","author":"Inthavong","year":"2011","journal-title":"Comput. Fluids"},{"issue":"8","key":"10.1016\/j.compbiomed.2021.105150_bib69","doi-asserted-by":"crossref","first-page":"492","DOI":"10.3109\/08958378.2012.694494","article-title":"Local deposition fractions of ultrafine particles in a human nasal-sinus cavity CFD model","volume":"24","author":"Ge","year":"2012","journal-title":"Inhal. Toxicol."},{"issue":"6","key":"10.1016\/j.compbiomed.2021.105150_bib70","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/annhyg\/mew018","article-title":"Transport and deposition of welding fume agglomerates in a realistic human nasal airway","volume":"60","author":"Tian","year":"2016","journal-title":"Ann. Occup. Hyg."},{"key":"10.1016\/j.compbiomed.2021.105150_bib71","doi-asserted-by":"crossref","first-page":"5562","DOI":"10.1016\/j.ijheatmasstransfer.2008.04.037","article-title":"Numerical predictions of submicrometer aerosol deposition in the nasal cavity using a novel drift flux approach","volume":"51","author":"Xi","year":"2008","journal-title":"Int. J. Heat Mass Tran."},{"issue":"10","key":"10.1016\/j.compbiomed.2021.105150_bib72","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.medengphy.2010.08.012","article-title":"Micron particle deposition in a tracheobronchial airway model under different breathing conditions","volume":"32","author":"Inthavong","year":"2010","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.compbiomed.2021.105150_bib73","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S0021-8502(02)00044-7","article-title":"The influence of breathing patterns on on particle deposition in a nasal replica cast","volume":"33","author":"Haubermann","year":"2002","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.compbiomed.2021.105150_bib74","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jaerosci.2015.09.002","article-title":"Transport and deposition of nano-fibers in human upper tracheobronchial airways","volume":"91","author":"Tian","year":"2016","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.compbiomed.2021.105150_bib75","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jaerosci.2013.12.008","article-title":"CFD simulation of total and regional fiber deposition in human nasal cavities","volume":"69","author":"Dastan","year":"2013","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.compbiomed.2021.105150_bib76","doi-asserted-by":"crossref","first-page":"105908","DOI":"10.1016\/j.jaerosci.2021.105908","article-title":"Microfiber transport characterization in human nasal cavity \u2013 effect of fiber length","volume":"160","author":"Li","year":"2022","journal-title":"J. Aerosol Sci."},{"key":"10.1016\/j.compbiomed.2021.105150_bib77","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jbiomech.2017.08.031","article-title":"Computational modeling and validation of human nasal airflow under various breathing conditions","volume":"64","author":"Li","year":"2017","journal-title":"J. Biomech."},{"key":"10.1016\/j.compbiomed.2021.105150_bib78","series-title":"Comparative Anatomy and Histology","first-page":"71","article-title":"6 - nose, sinus, pharynx, and larynx","author":"Harkema","year":"2012"},{"issue":"8","key":"10.1016\/j.compbiomed.2021.105150_bib79","doi-asserted-by":"crossref","first-page":"394","DOI":"10.3109\/08958378.2015.1066904","article-title":"Olfactory deposition of inhaled nanoparticles in humans","volume":"27","author":"Garcia","year":"2015","journal-title":"Inhal. Toxicol."},{"issue":"2\u20133","key":"10.1016\/j.compbiomed.2021.105150_bib80","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.resp.2011.07.009","article-title":"Correlation of nasal morphology to air-conditioning and clearance function","volume":"179","author":"White","year":"2011","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"3","key":"10.1016\/j.compbiomed.2021.105150_bib81","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0720-048X(99)00142-4","article-title":"Paranasal sinuses and nasopharynx CT and MRI","volume":"33","author":"Sievers","year":"2000","journal-title":"Eur. J. Radiol."}],"container-title":["Computers in Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010482521009446?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010482521009446?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T13:12:13Z","timestamp":1671714733000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0010482521009446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":81,"alternative-id":["S0010482521009446"],"URL":"https:\/\/doi.org\/10.1016\/j.compbiomed.2021.105150","relation":{},"ISSN":["0010-4825"],"issn-type":[{"value":"0010-4825","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detailed comparison of anatomy and airflow dynamics in human and cynomolgus monkey nasal cavity","name":"articletitle","label":"Article Title"},{"value":"Computers in Biology and Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.compbiomed.2021.105150","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105150"}}