{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T10:52:45Z","timestamp":1681296765159},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,8,24]],"date-time":"2010-08-24T00:00:00Z","timestamp":1282608000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Theory Biosci."],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1007\/s12064-010-0105-9","type":"journal-article","created":{"date-parts":[[2010,8,23]],"date-time":"2010-08-23T08:36:49Z","timestamp":1282552609000},"page":"5-18","source":"Crossref","is-referenced-by-count":6,"title":["Systemic investigation of a brain-centered model of the human energy metabolism"],"prefix":"10.1007","volume":"130","author":[{"given":"Britta","family":"G\u00f6bel","sequence":"first","affiliation":[]},{"given":"Dirk","family":"Langemann","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2010,8,24]]},"reference":[{"key":"105_CR1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1088\/0031-9155\/9\/2\/307","volume":"9","author":"E Ackerman","year":"1964","unstructured":"Ackerman E (1964) A mathematical model of the glucose-tolerance test. Phys Med Biol 9:203\u2013213","journal-title":"Phys Med Biol"},{"key":"105_CR2","volume-title":"Fractals everywhere","author":"M Barnsley","year":"1993","unstructured":"Barnsley M (1993) Fractals everywhere. Morgan Kaufmann, San Francisco"},{"key":"105_CR3","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1172\/JCI110398","volume":"68","author":"R Bergman","year":"1981","unstructured":"Bergman R, Phillips L, Cobelli C (1981) Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 68:1456\u20131467","journal-title":"J Clin Invest"},{"key":"105_CR4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-2006-924028","volume":"28","author":"T Bobbert","year":"2007","unstructured":"Bobbert T, Wegewitz U, Brechtel L, Freudenberg M, Mai K, Moehlig M, Diederich S, Ristow M, Rochlitz H, Pfeiffer AFH, Spranger J (2007) Adiponectin oligomers in human serum during acute and chronic exercise: Relation to lipid metabolism and insulin sensitivity. Int J Sports Med 28:1\u20138","journal-title":"Int J Sports Med"},{"key":"105_CR5","volume-title":"Basic neurochemistry: molecular, cellular and medical aspects","author":"D Clark","year":"1999","unstructured":"Clark D, Sokoloff L (1999) Basic neurochemistry: molecular, cellular and medical aspects. Lippincott Williams & Wilkins, Philadelphia"},{"key":"105_CR6","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10867-009-9134-3","volume":"35","author":"M Conrad","year":"2009","unstructured":"Conrad M, Hubold C, Fischer B, Peters A (2009) Modeling the hypothalamus\u2013pituitary\u2013adrenal system: homeostasis by interacting positive and negative feedback. J Biol Phys 35:149\u2013162","journal-title":"J Biol Phys"},{"key":"105_CR7","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.jtbi.2010.02.033","volume":"264","author":"B G\u00f6bel","year":"2010","unstructured":"G\u00f6bel B, Langemann D, Oltmanns K, Chung M (2010) Compact energy metabolism model: brain controlled energy supply. J Theor Biol 264:1214\u20131224","journal-title":"J Theor Biol"},{"key":"105_CR8","volume-title":"Nonlinear oscillations, dynamical systems and bifurcations of vector fields","author":"J Guckenheimer","year":"2002","unstructured":"Guckenheimer J, Holmes P (2002) Nonlinear oscillations, dynamical systems and bifurcations of vector fields. Springer, New York"},{"key":"105_CR9","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4612-4192-8","volume-title":"Differential equations: a dynamical systems approach\u2014higher-dimensional systems","author":"JH Hubbard","year":"1995","unstructured":"Hubbard JH, West BH (1995) Differential equations: a dynamical systems approach\u2014higher-dimensional systems. Springer, New York"},{"key":"105_CR10","volume-title":"Dynamical systems. Examples of complex behaviour","author":"J Jost","year":"2005","unstructured":"Jost J (2005) Dynamical systems. Examples of complex behaviour. Springer, Berlin"},{"key":"105_CR11","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1098\/rspb.1953.0009","volume":"140","author":"G Kennedy","year":"1953","unstructured":"Kennedy G (1953) The role of depot fat in the hypothalamic control of food intake in the rat. Proc R Soc Lond B Biol Sci 140:578\u2013592","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"105_CR12","volume-title":"Nonlinear systems","author":"HK Khalil","year":"2002","unstructured":"Khalil HK (2002) Nonlinear systems. Prentice Hall, Upper Saddle River"},{"key":"105_CR13","first-page":"87","volume":"7","author":"M Krieger","year":"1921","unstructured":"Krieger M (1921) \u00dcber die Atrophie menschlicher Organe bei Inanition (German: about the atrophy of human organs under inanition). Z Angew Anat Konstitutionsl 7:87\u2013134","journal-title":"Z Angew Anat Konstitutionsl"},{"key":"105_CR14","unstructured":"Langemann D (2007) Selfish-brain theory: mathematical challenges in the top-down analysis of metabolic supply chains. In: Grundy J et\u00a0al (eds) Proceedings of the tutorials, posters, panels and industrial contributions at the 26th International Conference on Conceptual Modeling\u2014ER 2007 Auckland, New Zealand, CRPIT 83, ACS, pp 39\u201349"},{"key":"105_CR15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s10867-008-9087-y","volume":"34","author":"D Langemann","year":"2008","unstructured":"Langemann D, Peters A (2008) Deductive functional assignment of elements in appetite regulation. J Biol Phys 34:413\u2013424","journal-title":"J Biol Phys"},{"key":"105_CR16","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.brainres.2008.01.097","volume":"1207","author":"D Langemann","year":"2008","unstructured":"Langemann D, Pellerin L, Peters A (2008) Making sense of AMPA receptor trafficking by modeling molecular mechanisms of synaptic plasticity. Brain Res 1207:60\u201372","journal-title":"Brain Res"},{"key":"105_CR17","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0166-2236(99)01465-4","volume":"22","author":"S Maren","year":"1999","unstructured":"Maren S (1999) Long-term potentiation in the amygdala: a mechanism for emotional learning and memory. Trends Neurosci 22:561\u2013567","journal-title":"Trends Neurosci"},{"key":"105_CR18","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1056\/NEJM195307022490104","volume":"249","author":"J Mayer","year":"1953","unstructured":"Mayer J (1953) Glucostatic mechanism of regulation of food intake. N Engl J Med 249:13\u201316","journal-title":"N Engl J Med"},{"key":"105_CR19","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/nature05026","volume":"443","author":"G Morton","year":"2006","unstructured":"Morton G, Cummings D, Baskin D, Barsh GS, Schwartz M (2006) Central nervous system control of food intake and body weight. Nature 443:289\u2013295","journal-title":"Nature"},{"key":"105_CR20","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4613-0003-8","volume-title":"Differential equations and dynamical systems","author":"L Perko","year":"2001","unstructured":"Perko L (2001) Differential equations and dynamical systems. Springer, New York"},{"issue":"2","key":"105_CR21","first-page":"1","volume":"1","author":"A Peters","year":"2009","unstructured":"Peters A, Langemann D (2009) Build-ups in the supply of the brain: on neuroenergetic cause of obesity and type 2 diabetes. Front Neuroenergetics 1(2):1\u201315","journal-title":"Front Neuroenergetics"},{"key":"105_CR22","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.neubiorev.2004.03.002","volume":"28","author":"A Peters","year":"2004","unstructured":"Peters A, Schweiger U, Pellerin L, Hubold C, Oltmanns K, Conrad M, Schultes B, Born J, Fehm H (2004) The selfish brain: competition for energy resources. Neurosci Biobehav Rev 28:143\u2013180","journal-title":"Neurosci Biobehav Rev"},{"key":"105_CR23","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.pneurobio.2006.12.004","volume":"81","author":"A Peters","year":"2007","unstructured":"Peters A, Pellerin L, Dallmann M, Oltmanns K, Schweiger U, Born J, Fehm H (2007) Causes of obesity\u2014looking beyond the hypothalamus. Prog Neurobiol 81:134\u2013143","journal-title":"Prog Neurobiol"},{"key":"105_CR24","unstructured":"Reilly T, Secher N, Snell P, Williams C (eds) (1990) Physiology of sports. E and FN Spon, London"},{"key":"105_CR25","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1152\/physrev.00015.2004","volume":"85","author":"S Stanley","year":"2005","unstructured":"Stanley S, Wynne K, McGowan B, Bloom S (2005) Hormonal regulation of food intake. Physiol Rev 85:1131\u20131158","journal-title":"Physiol Rev"},{"key":"105_CR26","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11538-005-9008-1","volume":"68","author":"L Vatov","year":"2006","unstructured":"Vatov L, Kizner Z, Ruppin E, Meilin S, Manor T, Mayevsky A (2006) Modeling brain energy metabolism and function: a multiparametric monitoring approach. Bull Math Biol 68:275\u2013291","journal-title":"Bull Math Biol"},{"key":"105_CR27","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-86405-6","volume-title":"Differential and integral inequalities","author":"W Walter","year":"1970","unstructured":"Walter W (1970) Differential and integral inequalities. Springer, Berlin"},{"key":"105_CR28","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/372425a0","volume":"372","author":"Y Zhang","year":"1994","unstructured":"Zhang Y, Proenca R, Maffei N, Barone M, Leopold L, Friedman J (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372:425\u2013432","journal-title":"Nature"}],"container-title":["Theory in Biosciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12064-010-0105-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12064-010-0105-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12064-010-0105-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T03:33:22Z","timestamp":1559446402000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12064-010-0105-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,24]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["105"],"URL":"https:\/\/doi.org\/10.1007\/s12064-010-0105-9","relation":{},"ISSN":["1431-7613","1611-7530"],"issn-type":[{"value":"1431-7613","type":"print"},{"value":"1611-7530","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,24]]}}}