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When the correlation structure between quality characteristics is ignored and profiles are monitored separately then misleading results could be expected. Hence, developing methods to account for this multivariate structure is required. In this paper, we specifically focus on phase I monitoring of multivariate multiple linear regression profiles and develop four methods for this purpose. The performance of the developed methods is compared through simulation studies in terms of probability of a signal. In addition, a diagnostic scheme to find the out\u2010of\u2010control samples is developed. Finally, the application of the proposed methods is illustrated using a calibration application at the National Aeronautics and Space Administration (NASA) Langley Research Center. Copyright \u00a9 2009 John Wiley & Sons, Ltd.<\/jats:p>","DOI":"10.1002\/qre.1066","type":"journal-article","created":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T16:46:04Z","timestamp":1251823564000},"page":"291-303","source":"Crossref","is-referenced-by-count":82,"title":["Statistical monitoring of multivariate multiple linear regression profiles in phase I with calibration application"],"prefix":"10.1002","volume":"26","author":[{"given":"R.","family":"Noorossana","sequence":"first","affiliation":[]},{"given":"M.","family":"Eyvazian","sequence":"additional","affiliation":[]},{"given":"Amirhossein","family":"Amiri","sequence":"additional","affiliation":[]},{"given":"Mahmoud A.","family":"Mahmoud","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2009,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(98)00094-6"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/00224065.2000.11980027"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1198\/004017004000000455"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/00224065.2004.11980276"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/qre.711"},{"key":"e_1_2_1_7_2","volume-title":"Introduction to Statistical Quality Control","author":"Montgomery DC","year":"2005"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-65132007000300002"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1198\/004017007000000164"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/00224065.2003.11980225"},{"key":"e_1_2_1_11_2","unstructured":"NoorossanaR AmiriA VaghefiSA RoghanianE.Monitoring quality characteristics using linear profile. 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