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However, there are some limitations of 1<\/jats:sup>H\u2010MRSI preventing its wider use in the clinics, including the spectral quality issues, partial volume effect and chemical shift artifact. Additionally, it is necessary to create metabolite maps for analyzing spectral data along with other MRI modalities. In this study, a MATLAB\u2010based open\u2010source data analysis software for three\u2010dimensional 1<\/jats:sup>H\u2010MRSI, called Oryx\u2010MRSI, which includes modules for visualization of raw 1<\/jats:sup>H\u2010MRSI data and LCModel outputs, chemical shift correction, tissue fraction calculation, metabolite map production, and registration onto standard MNI152 brain atlas while providing automatic spectral quality control, is presented. Oryx\u2010MRSI implements region of interest analysis at brain parcellations defined on MNI152 brain atlas. All generated metabolite maps are stored in NIfTI format. 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