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It is the second leading cause of cancer\u2010related deaths in the United States. Stapled anastomosis is a rapid treatment for colorectal cancer and other intestinal diseases and has become an integral part of routine surgical practice. However, to the best of our knowledge, there is no existing work simulating intestinal anastomosis that often involves sophisticated soft tissue manipulations such as cutting and stitching. In this paper, for the first time, we propose a novel split and join<\/jats:italic> approach to simulate a side\u2010to\u2010side stapled intestinal anastomosis in virtual reality. We mimic the intestine model using a new hybrid representation\u2014a grid\u2010linked particles model for physics simulation and a surface mesh for rendering. The proposed split and join<\/jats:italic> operations handle the updates of both the grid\u2010linked particles model and the surface mesh during the anastomosis procedure. The simulation results demonstrate the feasibility of the proposed approach in simulating intestine models and the side\u2010to\u2010side anastomosis operation.<\/jats:p>","DOI":"10.1002\/cav.2151","type":"journal-article","created":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T06:03:50Z","timestamp":1677996230000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Split and join: An efficient approach for simulating stapled intestinal anastomosis in virtual reality"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"http:\/\/orcid.org\/0000-0002-0467-6628","authenticated-orcid":false,"given":"Di","family":"Qi","sequence":"first","affiliation":[{"name":"Dale E. and Sara Ann Fowler School of Engineering Chapman University Orange California USA"}]},{"given":"Suvranu","family":"De","sequence":"additional","affiliation":[{"name":"College of Engineering Florida A&M University\u00a0\u2013\u00a0Florida State University Tallahassee Florida USA"}]}],"member":"311","published-online":{"date-parts":[[2023,2,27]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"U.S. Department of Health and Human Services Center for Disease Control and Prevention and National Cancer Institute.U.S. Cancer Statistics [Online]; 2022. 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