An easy synthesis of autofluorescent alloyed silver-gold nanoparticles
- PMID: 32262078
- DOI: 10.1039/c4tb01010h
An easy synthesis of autofluorescent alloyed silver-gold nanoparticles
Abstract
A one-pot synthesis of fluorescent bimetallic silver-gold nanoparticles in aqueous medium is presented. Carboxylic acid-functionalized nanoparticles were prepared with different metal compositions from 90 : 10 to 10 : 90 (n : n) for silver : gold with a diameter of 1.8 ± 0.4 nm. Pure silver and gold nanoparticles were prepared for comparison. Spectroscopic analyses showed that the ligand, i.e. 11-mercaptoundecanoic acid, binds to the particle surface by the thiol group, leaving the carboxylic acid accessible for further functionalization, e.g. by suitable coupling reactions. Nanoparticles with a silver content up to 60 : 40 showed autofluorescence with a large Stokes shift of about 250-300 nm (maximum wavelength of the emission between 608 nm and 645 nm). The intracellular localization of bimetallic silver-gold nanoparticles was studied in HeLa cells by confocal laser scanning microscopy (CLSM). The alloyed silver-gold nanoparticles showed no significant cytotoxicity at a metal concentration of 5 μg mL-1 for 24 h, but were cytotoxic to some degree at 50 μg mL-1 at higher silver content.
Similar articles
-
Synthesis, characterization and in vitro effects of 7 nm alloyed silver-gold nanoparticles.Beilstein J Nanotechnol. 2015 May 27;6:1212-20. doi: 10.3762/bjnano.6.124. eCollection 2015. Beilstein J Nanotechnol. 2015. PMID: 26171298 Free PMC article.
-
Ultrasmall gold and silver/gold nanoparticles (2 nm) as autofluorescent labels for poly(D,L-lactide-co-glycolide) nanoparticles (140 nm).J Mater Sci Mater Med. 2020 Nov 28;31(12):117. doi: 10.1007/s10856-020-06449-8. J Mater Sci Mater Med. 2020. PMID: 33247365 Free PMC article.
-
Eco-friendly microwave-assisted green and rapid synthesis of well-stabilized gold and core-shell silver-gold nanoparticles.Carbohydr Polym. 2016 Jan 20;136:1128-36. doi: 10.1016/j.carbpol.2015.10.003. Epub 2015 Oct 9. Carbohydr Polym. 2016. PMID: 26572455
-
Optical response of Ag-Au bimetallic nanoparticles to electron storage in aqueous medium.J Nanosci Nanotechnol. 2008 Jun;8(6):3003-7. doi: 10.1166/jnn.2008.157. J Nanosci Nanotechnol. 2008. PMID: 18681038
-
Gold and Silver Nanoparticles for Applications in Theranostics.Curr Top Med Chem. 2016;16(27):3069-3102. doi: 10.2174/1568026616666160715163346. Curr Top Med Chem. 2016. PMID: 27426869 Review.
Cited by
-
Artificial neural network approach for prediction of AuNPs biosynthesis by Streptomyces flavolimosus, characterization, antitumor potency in-vitro and in-vivo against Ehrlich ascites carcinoma.Sci Rep. 2023 Aug 4;13(1):12686. doi: 10.1038/s41598-023-39177-4. Sci Rep. 2023. PMID: 37542154 Free PMC article.
-
An in situ SAXS investigation of the formation of silver nanoparticles and bimetallic silver-gold nanoparticles in controlled wet-chemical reduction synthesis.Nanoscale Adv. 2019 Nov 25;2(1):225-238. doi: 10.1039/c9na00569b. eCollection 2020 Jan 22. Nanoscale Adv. 2019. PMID: 36133991 Free PMC article.
-
An Aptasensor Based on a Flexible Screen-Printed Silver Electrode for the Rapid Detection of Chlorpyrifos.Sensors (Basel). 2022 Apr 2;22(7):2754. doi: 10.3390/s22072754. Sensors (Basel). 2022. PMID: 35408368 Free PMC article.
-
One Pot Synthesis of PEGylated Bimetallic Gold-Silver Nanoparticles for Imaging and Radiosensitization of Oral Cancers.Int J Nanomedicine. 2021 Oct 21;16:7103-7121. doi: 10.2147/IJN.S329762. eCollection 2021. Int J Nanomedicine. 2021. PMID: 34712044 Free PMC article.
-
Pathways for Oral and Rectal Delivery of Gold Nanoparticles (1.7 nm) and Gold Nanoclusters into the Colon: Enteric-Coated Capsules and Suppositories.Molecules. 2021 Aug 21;26(16):5069. doi: 10.3390/molecules26165069. Molecules. 2021. PMID: 34443657 Free PMC article.
LinkOut - more resources
Full Text Sources
