Upper limb function in adults with Duchenne muscular dystrophy
- PMID: 21826385
- DOI: 10.2340/16501977-0841
Upper limb function in adults with Duchenne muscular dystrophy
Abstract
Objective: To determine upper limb function and associated factors in adults with Duchenne muscular dystrophy.
Design: Cross-sectional study.
Subjects: A sample of 70 men with Duchenne muscular dystrophy (age range 20-43 years).
Methods: General motor function and, in particular, upper limb distal motor function, were assessed with the Motor Function Measure. Muscle strength and range of motion of the upper limb were evaluated using hand-held dynamo-metry, manual muscle-testing and goniometry. Associations were studied using Spearman's correlation coefficients and multiple linear regression analysis.
Results: General motor function was severely impaired. Wide variability was found in distal motor function, muscle strength and range of motion of the upper limb, especially in early adulthood. Muscle strength and range of motion explained 76% of the variance in upper limb distal motor function.
Conclusion: This study illustrates a large variability in upper limb function in adult patients with Duchenne muscular dystrophy, and identifies muscle strength and range of motion as factors strongly associated with upper limb function. These results suggest that preserving muscle strength and range of motion in Duchenne patients might be relevant for a better outcome of distal motor function of the upper limb when adult.
Similar articles
-
Innovative methods to assess upper limb strength and function in non-ambulant Duchenne patients.Neuromuscul Disord. 2013 Feb;23(2):139-48. doi: 10.1016/j.nmd.2012.10.022. Epub 2012 Dec 5. Neuromuscul Disord. 2013. PMID: 23219352
-
Different types of upper extremity exercise training in Duchenne muscular dystrophy: effects on functional performance, strength, endurance, and ambulation.Muscle Nerve. 2015 May;51(5):697-705. doi: 10.1002/mus.24451. Epub 2015 Mar 5. Muscle Nerve. 2015. PMID: 25196721 Clinical Trial.
-
Manual ability and upper limb performance in nonambulatory stage of Duchenne muscular dystrophy.Arch Pediatr. 2020 Aug;27(6):304-309. doi: 10.1016/j.arcped.2020.06.007. Epub 2020 Jul 24. Arch Pediatr. 2020. PMID: 32718814
-
Evaluation of admittance control as an alternative to passive arm supports to increase upper extremity function for individuals with Duchenne muscular dystrophy.Muscle Nerve. 2020 Jun;61(6):692-701. doi: 10.1002/mus.26848. Muscle Nerve. 2020. PMID: 32128840 Review.
-
Duchenne muscle activity evaluation and muscle function preservation: is it possible a prophylactic strategy?Obes Rev. 2008 Mar;9(2):121-39. doi: 10.1111/j.1467-789X.2007.00423.x. Epub 2007 Nov 23. Obes Rev. 2008. PMID: 18034791 Review.
Cited by
-
Improvements in motor tasks through the use of smartphone technology for individuals with Duchenne muscular dystrophy.Neuropsychiatr Dis Treat. 2017 Aug 18;13:2209-2217. doi: 10.2147/NDT.S125466. eCollection 2017. Neuropsychiatr Dis Treat. 2017. PMID: 28860778 Free PMC article.
-
Development and evaluation of a passive trunk support system for Duchenne muscular dystrophy patients.J Neuroeng Rehabil. 2018 Mar 14;15(1):22. doi: 10.1186/s12984-018-0353-3. J Neuroeng Rehabil. 2018. PMID: 29540235 Free PMC article.
-
Gastrocnemius medialis muscle architecture and physiological cross sectional area in adult males with Duchenne muscular dystrophy.J Musculoskelet Neuronal Interact. 2015 Jun;15(2):154-60. J Musculoskelet Neuronal Interact. 2015. PMID: 26032207 Free PMC article.
-
Reliability, validity and description of timed performance of the Jebsen-Taylor Test in patients with muscular dystrophies.Braz J Phys Ther. 2018 May-Jun;22(3):190-197. doi: 10.1016/j.bjpt.2017.09.010. Epub 2017 Dec 8. Braz J Phys Ther. 2018. PMID: 29292138 Free PMC article.
-
Converging Robotic Technologies in Targeted Neural Rehabilitation: A Review of Emerging Solutions and Challenges.Sensors (Basel). 2021 Mar 16;21(6):2084. doi: 10.3390/s21062084. Sensors (Basel). 2021. PMID: 33809721 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
