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Comparative Study
. 2008 Jan;22(1):87-90.
doi: 10.1038/sj.eye.6702947. Epub 2007 Sep 28.

Comparison of macular hole size measured by optical coherence tomography, digital photography, and clinical examination

S E Benson  1 , P G Schlottmann, C Bunce, D G Charteris
Affiliations
Comparative Study

Comparison of macular hole size measured by optical coherence tomography, digital photography, and clinical examination

S E Benson et al. Eye (Lond). 2008 Jan.

Abstract

Aim: To report on the agreement of macular hole size as measured using optical coherence tomography (OCT), Topcon digital photography, and surgeon estimate on clinical examination.

Methods: Observational cohort series of patients who underwent macular hole surgery over an 18-month period. Patients had OCT scan and digital fundus photographs preoperatively. At operation the surgeon estimated the size of macular hole. The agreement between methods was assessed using the technique described by Bland and Altman.

Results: There was good repeatability of photographic and OCT assessment and no evidence of systematic bias between repeated macular hole measurement by digital photography (P=0.36) or by OCT (P=0.58). There was evidence of systematic bias between photographic and surgeon measurements (P<0.001), and between OCT and surgeon (P<0.001) with photographic and OCT assessment being greater. There was also evidence of bias between OCT and photographic measurements with photographic measurement tending to be greater than the OCT measurement for smaller holes and lower for larger holes (P=0.02).

Conclusions: OCT and Topcon digital photography have good repeatability for measurement of macular hole size. Both these methods measured larger hole sizes compared to surgeon estimate. Digital photography and OCT methods did not agree.

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