Fishing for Age-Related Visual System Mutants: Behavioral Screening of Retinal Degeneration Genes in Zebrafish

Title: Fishing for Age-Related Visual System Mutants: Behavioral Screening of Retinal Degeneration Genes in Zebrafish

Volume: 3 Issue: 1

Author(s): Lei Li, Yuhao Li, Dongyan Chen, Jinping Shao, Xin le Li and Chen Xu

Affiliation:

Keywords: Neural degeneration, zebrafish, retina, mutation

Abstract: The zebrafish (Danio rerio) has recently become a mainstream model system for genetic studies of human diseases, such as neurological degenerative diseases, heart diseases, immuno-system disorders, etc. In this article, we will review some recent findings of the usefulness of zebrafish as a model vertebrate for behavioral screening of mutations in vertebrate visual system, for example, genes involved in age-related retinal degeneration.

Cite this article as:

Li Lei, Li Yuhao, Chen Dongyan, Shao Jinping, Li le Xin and Xu Chen, Fishing for Age-Related Visual System Mutants: Behavioral Screening of Retinal Degeneration Genes in Zebrafish, Current Aging Science 2010; 3 (1) . https://dx.doi.org/10.2174/1874609811003010043