Direct Oral Anticoagulants use in Patients with Stable Coronary Artery Disease, Acute Coronary Syndrome or Undergoing Percutaneous Coronary Intervention | Bentham Science
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Review Article

Direct Oral Anticoagulants use in Patients with Stable Coronary Artery Disease, Acute Coronary Syndrome or Undergoing Percutaneous Coronary Intervention

Author(s): Marios Sagris*, Panagiotis Theofilis, Angelos Papanikolaou, Alexios S. Antonopoulos, Constantinos Tsioufis and Dimitris Tousoulis

Volume 29, Issue 35, 2023

Published on: 30 November, 2023

Page: [2787 - 2794] Pages: 8

DOI: 10.2174/0113816128259508231118141831

Price: $65

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Abstract

The investigation for the optimal anticoagulation strategy for patients with stable coronary artery disease, acute coronary syndromes, and undergoing percutaneous coronary intervention constitutes a great challenge for physicians and is a field of extensive research. Although aspirin is commonly recommended as a protective measure for all patients with coronary artery disease and dual antiplatelet therapy for those undergoing procedures, such as percutaneous coronary intervention or coronary artery bypass graft surgery, the risk of recurrent cardiovascular events remains significant. In this context, the shortcomings associated with the use of vitamin K antagonists have led to the assessment of direct oral anticoagulants as promising alternatives. This review will explore and provide a comprehensive analysis of the existing data regarding the use of direct oral anticoagulants in patients with stable coronary artery disease or acute coronary syndrome, as well as their effectiveness in those undergoing percutaneous coronary intervention or coronary artery bypass graft surgery.

Keywords: Direct oral anticoagulant, coronary artery disease, acute coronary syndrome, percutaneous coronary intervention, coronary artery bypass graft, surgery, dual antiplatelet therapy.

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