Abstract
Background: Synovial chondromatosis is an uncommon benign condition characterized by synovial membrane proliferation and metaplasia. Synovial chondromatosis cases in patients with rheumatoid arthritis have been reported. However, involvement of the glenohumeral joint is rare.
Case Presentation: We herein report a case of a rare association of synovial chondromatosis involving the shoulder in a rheumatoid arthritis patient. The symptoms have improved with anti-tumor necrosis factor drugs. Consequently, there was no need for invasive therapy to treat synovial chondromatosis.
Conclusion: Synovial chondromatosis can be aggressive and destructive. More trials are needed to establish a better clinical diagnostic strategy and pharmacological management.
Keywords: Chondromatosis, synovial, rheumatoid arthritis, joint loose bodies, shoulder joint, tumor necrosis factor inhibitors.
Graphical Abstract
[1]
Sim FH. Synovial proliferative disorders: Role of synovectomy. Arthroscopy 1985; 1(3): 198-204.
[http://dx.doi.org/10.1016/S0749-8063(85)80012-8] [PMID: 4096771]
[http://dx.doi.org/10.1016/S0749-8063(85)80012-8] [PMID: 4096771]
[2]
Milgram JW. Synovial osteochondromatosis. J Bone Joint Surg Am 1977; 59(6): 792-801.
[http://dx.doi.org/10.2106/00004623-197759060-00013] [PMID: 908703]
[http://dx.doi.org/10.2106/00004623-197759060-00013] [PMID: 908703]
[3]
Aydogan NH, Kocadal O, Ozmeric A, Aktekin CN. Arthroscopic treatment of a case with concomitant subacromial and subdeltoid synovial chondromatosis and labrum tear. Case Rep Orthop 2013; 2013: 1-4.
[http://dx.doi.org/10.1155/2013/636747] [PMID: 24383030]
[http://dx.doi.org/10.1155/2013/636747] [PMID: 24383030]
[4]
Mata BA, Eward WC, Brigman BE. Pancarpal synovial and tenosynovial chondromatosis in a 65-year-old man: A highly unusual presentation of a common condition. Am J Orthop 2013; 42(8): E60-3.
[PMID: 24078960]
[PMID: 24078960]
[5]
Hamilton A, Davis RI, Nixon JR. Synovial chondrosarcoma complicating synovial chondromatosis. Report of a case and review of the literature. J Bone Joint Surg Am 1987; 69(7): 1084-8.
[http://dx.doi.org/10.2106/00004623-198769070-00019] [PMID: 3654701]
[http://dx.doi.org/10.2106/00004623-198769070-00019] [PMID: 3654701]
[6]
Ryan RS, Harris AC, O’Connell JX, Munk PL. Synovial osteochondromatosis: The spectrum of imaging findings. Australas Radiol 2005; 49(2): 95-100.
[http://dx.doi.org/10.1111/j.1440-1673.2005.01416.x] [PMID: 15845042]
[http://dx.doi.org/10.1111/j.1440-1673.2005.01416.x] [PMID: 15845042]
[7]
Ballard R, Weiland LH. Synovial chondromatosis of the temporomandibular joint. Cancer 1972; 30(3): 791-5.
[http://dx.doi.org/10.1002/1097-0142(197209)30:3<791:AID-CNCR2820300329>3.0.CO;2-D] [PMID: 5075361]
[http://dx.doi.org/10.1002/1097-0142(197209)30:3<791:AID-CNCR2820300329>3.0.CO;2-D] [PMID: 5075361]
[8]
Neumann JA, Garrigues GE, Brigman BE, Eward WC. Synovial chondromatosis. JBJS Rev 2016; 4(5): 1.
[http://dx.doi.org/10.2106/JBJS.RVW.O.00054] [PMID: 27490219]
[http://dx.doi.org/10.2106/JBJS.RVW.O.00054] [PMID: 27490219]
[9]
Tahmasebi MN, Bashti K, Sobhan M, Ghorbani G. Bilateral synovial knee chondromatosis in a patient with rheumatoid arthritis: Case-report and literature review. Arch Bone Jt Surg 2014; 2(4): 260-4.
[PMID: 25692156]
[PMID: 25692156]
[10]
Padhan P, Ahmed S. Synovial chondromatosis. N Engl J Med 2019; 381(14): 1364-4.
[http://dx.doi.org/10.1056/NEJMicm1813672] [PMID: 31577878]
[http://dx.doi.org/10.1056/NEJMicm1813672] [PMID: 31577878]
[11]
Kandasamy J, Subramanian AMRP, Chokkapa PR, et al. Polyarticular osteochondromatosis. J Clin Rheumatol 2009; 15(3): 143-4.
[http://dx.doi.org/10.1097/RHU.0b013e3181a023a7] [PMID: 19300280]
[http://dx.doi.org/10.1097/RHU.0b013e3181a023a7] [PMID: 19300280]
[12]
Bhadu D, Das SK, Dhakad U, Sharma M, Srivastava D, Tripathy SR. Synovial chondromatosis involving multiple joints in rheumatoid arthritis: A case report review of the literature. Int J Rheum Dis 2017; 20(12): 2148-51.
[http://dx.doi.org/10.1111/1756-185X.12887] [PMID: 27126892]
[http://dx.doi.org/10.1111/1756-185X.12887] [PMID: 27126892]
[13]
Witwity T, Uhlmann R, Nagy MH, Bhasin VB, Bahgat MM, Singh AK. Shoulder rheumatoid arthritis associated with chondromatosis, treated by arthroscopy. Arthroscopy 1991; 7(2): 233-6.
[http://dx.doi.org/10.1016/0749-8063(91)90112-B] [PMID: 2069636]
[http://dx.doi.org/10.1016/0749-8063(91)90112-B] [PMID: 2069636]
[14]
Bingöl U, Altan L, Dinçsahin E, Yurtkuran M. Chondromatosis in subacromial bursae. J Rheumatol 2002; 29(7): 1559-60.
[PMID: 12136921]
[PMID: 12136921]
[15]
Kiritsi O, Tsitas K, Grollios G. A case of idiopathic bursal synovial chondromatosis resembling rheumatoid arthritis. Hippokratia 2009; 13(1): 61-3.
[PMID: 19240826]
[PMID: 19240826]
[16]
Buess E, Friedrich B. Synovial chondromatosis of the glenohumeral joint: A rare condition. Arch Orthop Trauma Surg 2001; 121(1-2): 109-11.
[http://dx.doi.org/10.1007/s004020000168] [PMID: 11195106]
[http://dx.doi.org/10.1007/s004020000168] [PMID: 11195106]
[17]
Chillemi C, Marinelli M, de Cupis V. Primary synovial chondromatosis of the shoulder: Clinical, arthroscopic and histopathological aspects. Knee Surg Sports Traumatol Arthrosc 2005; 13(6): 483-8.
[http://dx.doi.org/10.1007/s00167-004-0608-3] [PMID: 15726326]
[http://dx.doi.org/10.1007/s00167-004-0608-3] [PMID: 15726326]
[18]
Gasbarrini A, Biscaglia R, Donati D, Casadei R, Picci P. Synovial chondromatosis of the shoulder. A review of the literature and description of a clinical case. Chir Organi Mov 1997; 82(1): 73-81.
[PMID: 9269117]
[PMID: 9269117]
[19]
Jung KA, Kim SJ, Jeong JH. Arthroscopic treatment of synovial chondromatosis that possibly developed after open capsular shift for shoulder instability. Knee Surg Sports Traumatol Arthrosc 2007; 15(12): 1499-503.
[http://dx.doi.org/10.1007/s00167-007-0357-1] [PMID: 17581741]
[http://dx.doi.org/10.1007/s00167-007-0357-1] [PMID: 17581741]
[20]
Alexander JE, Holder JC, McConnell JR, Fontenot E Jr. Synovial osteochondromatosis. Am Fam Physician 1987; 35(2): 157-61.
[PMID: 3812170]
[PMID: 3812170]
[21]
Milgram JW. The classification of loose bodies in human joints. Clin Orthop Relat Res 1977; &NA(124): 282-91.
[http://dx.doi.org/10.1097/00003086-197705000-00039] [PMID: 598088]
[http://dx.doi.org/10.1097/00003086-197705000-00039] [PMID: 598088]
[22]
Campeau NG, Lewis BD. Ultrasound appearance of synovial osteochondromatosis of the shoulder. Mayo Clin Proc 1998; 73(11): 1079-81.
[http://dx.doi.org/10.4065/73.11.1079] [PMID: 9818043]
[http://dx.doi.org/10.4065/73.11.1079] [PMID: 9818043]
[23]
Frankel DA, Bargiela A, Bouffard JA, Craig JG, Shirazi KK, van Holsbeeck MT. Synovial joints: Evaluation of intraarticular bodies with US. Radiology 1998; 206(1): 41-4.
[http://dx.doi.org/10.1148/radiology.206.1.9423649] [PMID: 9423649]
[http://dx.doi.org/10.1148/radiology.206.1.9423649] [PMID: 9423649]
[25]
Kramer J, Recht M, Deely DM, et al. MR appearance of idiopathic synovial osteochondromatosis. J Comput Assist Tomogr 1993; 17(5): 772-6.
[http://dx.doi.org/10.1097/00004728-199309000-00020] [PMID: 8370833]
[http://dx.doi.org/10.1097/00004728-199309000-00020] [PMID: 8370833]
[26]
Mishra BN, Poudel RR, Jha A, Mainali N, Bhattarai M. Rheumatoid subacromial-subdeltoid bursitis with rice bodies: A case report. J Clin Orthop Trauma 2019; 10(3): 514-7.
[http://dx.doi.org/10.1016/j.jcot.2018.09.014] [PMID: 31061580]
[http://dx.doi.org/10.1016/j.jcot.2018.09.014] [PMID: 31061580]
[27]
Ji JH, Shafi M, Jeong DS. Secondary synovial chondromatosis of the shoulder. Knee Surg Sports Traumatol Arthrosc 2015; 23(9): 2624-7.
[http://dx.doi.org/10.1007/s00167-014-3024-3] [PMID: 24803015]
[http://dx.doi.org/10.1007/s00167-014-3024-3] [PMID: 24803015]
[28]
Yu S, Wu M, Zhou G, et al. Potential utility of anti‐TNF drugs in synovial chondromatosis associated with ankylosing spondylitis. Int J Rheum Dis 2019; 22(11): 2073-9.
[http://dx.doi.org/10.1111/1756-185X.13734] [PMID: 31647182]
[http://dx.doi.org/10.1111/1756-185X.13734] [PMID: 31647182]
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