Abstract
A green, efficient and operationally simple method for three-component synthesis of 1,2,3- trisubstituted pyrrole derivatives via an iodine-catalyzed tandem reaction has been developed, and a series of 1,2,3-trisubstituted pyrrole derivatives were synthesized from simple starting materials under neutral conditions, with good to excellent yields in short time. This method showcased the potential of great value as a mild, rapid, and general procedure for the synthesis of 1,2,3-trisubstituted pyrroles.
Keywords: 1, 2, 3-Trisubstituted pyrrole, iodocyclization, multicomponent reaction (MCR), tandem reaction.
Graphical Abstract
Call for Papers in Thematic Issues
Carbohydrates: Synthesis, properties and applications
This special issue on carbohydrates will the first of a series focused on the biomolecules, the following ones being amino acids / peptides, nucleosides / nucleotides, lipids. All the issues of the series will contain exclusively full-length reviews and mini-reviews on the given topic written by specialists working in technologically ...read more
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