Systemic impact of heavy metals and their role in cancer development: a review

L Parida, TN Patel - Environmental Monitoring and Assessment, 2023 - Springer
Heavy metals are well-recognised as environmental hazards due to their toxicity,
environmental persistence, and bioaccumulation in living organisms. Human health is a …

Arsenic-induced changes in miRNA expression in cancer and other diseases

APF Cardoso, KT Udoh, JC States - Toxicology and applied pharmacology, 2020 - Elsevier
Abstract miRNAs (miRNA) are essential players regulating gene expression affecting
cellular processes contributing to disease development. Dysregulated miRNA expression …

Microbiology of inorganic arsenic: from metabolism to bioremediation

S Yamamura, S Amachi - Journal of bioscience and bioengineering, 2014 - Elsevier
Arsenic (As) contamination of drinking water and soils poses a threat to a large number of
people worldwide, especially in Southeast Asia. The predominant forms of As in soils and …

Dose-response for assessing the cancer risk of inorganic arsenic in drinking water: the scientific basis for use of a threshold approach

JS Tsuji, ET Chang, PR Gentry, HJ Clewell… - Critical reviews in …, 2019 - Taylor & Francis
The biologic effects of inorganic arsenic predominantly involve reaction of the trivalent forms
with sulfhydryl groups in critical proteins in target cells, potentially leading to various …

Arsenic co-carcinogenesis: Inhibition of DNA repair and interaction with zinc finger proteins

X Zhou, RM Speer, L Volk, LG Hudson, KJ Liu - Seminars in cancer biology, 2021 - Elsevier
Arsenic is widely present in the environment and is associated with various population
health risks including cancers. Arsenic exposure at environmentally relevant levels …

Update of the risk assessment of inorganic arsenic in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2024 - Wiley Online Library
Abstract The European Commission asked EFSA to update its 2009 risk assessment on
arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the …

[HTML][HTML] Mitochondrial uncoupling proteins (UCPs) as key modulators of ROS homeostasis: A crosstalk between diabesity and male infertility?

BS Monteiro, L Freire-Brito, DF Carrageta, PF Oliveira… - Antioxidants, 2021 - mdpi.com
Uncoupling proteins (UCPs) are transmembrane proteins members of the mitochondrial
anion transporter family present in the mitochondrial inner membrane. Currently, six …

Endocrine disruptors and developmental origins of nonalcoholic fatty liver disease

LS Treviño, TA Katz - Endocrinology, 2018 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a growing epidemic worldwide, particularly in
countries that consume a Western diet, and can lead to life-threatening conditions such as …

[HTML][HTML] Expression and putative role of mitochondrial transport proteins in cancer

O Lytovchenko, ERS Kunji - Biochimica et Biophysica Acta (BBA) …, 2017 - Elsevier
Cancer cells undergo major changes in energy and biosynthetic metabolism. One of them is
the Warburg effect, in which pyruvate is used for fermentation rather for oxidative …

Impact of prenatal arsenic exposure on chronic adult diseases

JL Young, L Cai, JC States - Systems biology in reproductive …, 2018 - Taylor & Francis
Exposure to environmental stressors during susceptible windows of development can result
in negative health outcomes later in life, a concept known as the Developmental Origins of …