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Contribution of inorganic and organic components to sorption of neutral and ionizable pharmaceuticals by sediment/soil

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Abstract

Our previous study showed that the sorption coefficient of certain polar pharmaceuticals to river sediment, especially particular amines, was unexpectedly high. Thus, we conducted sorption experiments of selected polar pharmaceuticals and pyrene derivatives, including amines, carboxylic acids, and neutral compounds, to model clay minerals, i.e., montmorillonite and kaolin, in addition to silica sands and humic substances. The contribution of each component was roughly estimated by simple fractionation of the individual sorption coefficients. Relatively high sorption coefficients (K d values) were found, especially for amines on clay minerals, which suggest that electrochemical affinity may play an important role. The estimated contribution percentage suggests a relatively large contribution from inorganic constituents, such as clay minerals, for silt loam soil; in contrast, organic components predominantly contribute for sandy river sediments. These findings could be the key to understanding not only the fate and transport but also bioavailability and environmental risks of pharmaceuticals, which are mostly polar and/or ionizable.

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Acknowledgments

The authors appreciate the assistance provided by Mr. Kentaro Wada of Tokushima Agriculture, Forestry, and Fisheries Technology Support Center for the measurement of the CEC values of the solid samples.

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Authors and Affiliations

  1. Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan

    Hiroshi Yamamoto, Kohei Takemoto, Ikumi Tamura, Norihiro Shin-oka, Takahiro Nakano, Masayo Nishida, Yuta Honda, Shigemi Moriguchi & Yudai Nakamura

  2. Research Center for Environmental Quality Management, Kyoto University, 1-1 Yumihama, Otsu, Shiga, Japan

    Kohei Takemoto

  3. National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki, 305-8506, Japan

    Ikumi Tamura

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  1. Hiroshi Yamamoto
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  2. Kohei Takemoto
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  3. Ikumi Tamura
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  4. Norihiro Shin-oka
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  5. Takahiro Nakano
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Correspondence to Hiroshi Yamamoto.

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Responsible editor: Philippe Garrigues

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Yamamoto, H., Takemoto, K., Tamura, I. et al. Contribution of inorganic and organic components to sorption of neutral and ionizable pharmaceuticals by sediment/soil. Environ Sci Pollut Res 25, 7250–7261 (2018). https://doi.org/10.1007/s11356-016-6471-1

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  • DOI: https://doi.org/10.1007/s11356-016-6471-1

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